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2026.
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A Theragnostic HIFU Transducer and System for Inherently Registered Imaging and Therapy
A Theragnostic HIFU Transducer and System for Inherently Registered Imaging and Therapy
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Plane wave imaging (11 angles, -10o to + 10o) with a transmitting frequency of 3.15 MHz was adopted to have the cross-sectional view of the two identical poles which were previously imaged by the VA method.
The B-mode imaging depth was about 6 cm, and the DAS beamforming was used to reconstruct the final image.
Contrast resolution of the VA imaging system was also tested by an in-vitro phantom.
Specifically, an agar-based tissue mimicking phantom containing four objects with different stiffness were fabricated and imaged by the proposed method.
The components of phantom material were the same as the one being fabricated for the previous experiment in Fig. 3(b), but there were four poles embedded in a single block.
The percentages of agar component in the four poles were 1%, 2%, 3% and 4% respectively to have different stiffness in the testing.
The contrast to noise ratios (CNR) between the four poles and the background area were calculated by the (17) [35].
Where ui and si is the mean value and standard deviation of the pixel amplitude within the selected region of interest (ROI), u0 and s0 the mean value and standard deviation of a selected background area.
Therapeutic Planning and Evaluation With the Upgraded HIFU-System.
Since the same HIFU transducer can be used both for imaging and for therapy, it needs no extra spatial registration between the two modalities, allowing the HIFU surgery to be conducted in a more accurate way.
Specifically, we first scan the region of interest under the VA imaging modality to get anatomical information of the tumor or any diseased tissues having different acoustic or mechanical properties.
The obtained image and its position indexes can then easily be used to guide the HIFU transducer to only treat the diseased region.
This concept could be better explained by illustrations in Fig. 4, in which it depicts a 'tumor' (the round shape) surrounded by healthy tissue.
After a raster scanning, a VA image of the object model as in Fig. 4(b) can be obtained, together with the raster scanning index (the dots in Fig. 4(b)).
We could move the programmed robot arm according to those indexes and increase the driving power to the therapeutic level to only ablate the 'tumor'.
Note that the VA image might be distorted as in Fig. 4(b) due to distortion of wave propagations in reality, but the proposed dual-mode strategy should be immune to some distortions since the imaging and the therapy share the same acoustic passage.
After the treatment, the raster scanning can be conducted again to get a second VA image to check whether the ablation took place in the desired positions as planned.
This evaluation procedure assumes that acoustic and mechanical properties of the damaged tissue are different from that of the unablated tissue.
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상세한 구문 분석을 보고 싶은 문장을 선택하세요.
1
Plane wave imaging (11 angles, -10o to + 10o) with a transmitting frequency of 3.15 MHz was adopted to have the cross-sectional view of the two identical poles which were previously imaged by the VA method.
2
The B-mode imaging depth was about 6 cm, and the DAS beamforming was used to reconstruct the final image.
3
Contrast resolution of the VA imaging system was also tested by an in-vitro phantom.
4
Specifically, an agar-based tissue mimicking phantom containing four objects with different stiffness were fabricated and imaged by the proposed method.
5
The components of phantom material were the same as the one being fabricated for the previous experiment in Fig. 3(b), but there were four poles embedded in a single block.
6
The percentages of agar component in the four poles were 1%, 2%, 3% and 4% respectively to have different stiffness in the testing.
7
The contrast to noise ratios (CNR) between the four poles and the background area were calculated by the (17) [35].
8
Where ui and si is the mean value and standard deviation of the pixel amplitude within the selected region of interest (ROI), u0 and s0 the mean value and standard deviation of a selected background area.
9
Therapeutic Planning and Evaluation With the Upgraded HIFU-System.
10
Since the same HIFU transducer can be used both for imaging and for therapy, it needs no extra spatial registration between the two modalities, allowing the HIFU surgery to be conducted in a more accurate way.
11
Specifically, we first scan the region of interest under the VA imaging modality to get anatomical information of the tumor or any diseased tissues having different acoustic or mechanical properties.
12
The obtained image and its position indexes can then easily be used to guide the HIFU transducer to only treat the diseased region.
13
This concept could be better explained by illustrations in Fig. 4, in which it depicts a 'tumor' (the round shape) surrounded by healthy tissue.
14
After a raster scanning, a VA image of the object model as in Fig. 4(b) can be obtained, together with the raster scanning index (the dots in Fig. 4(b)).
15
We could move the programmed robot arm according to those indexes and increase the driving power to the therapeutic level to only ablate the 'tumor'.
16
Note that the VA image might be distorted as in Fig. 4(b) due to distortion of wave propagations in reality, but the proposed dual-mode strategy should be immune to some distortions since the imaging and the therapy share the same acoustic passage.
17
After the treatment, the raster scanning can be conducted again to get a second VA image to check whether the ablation took place in the desired positions as planned.
18
This evaluation procedure assumes that acoustic and mechanical properties of the damaged tissue are different from that of the unablated tissue.
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지문에 사용된 특정 문장에 대한 궁금증은 해당 문장의 헬프fico쌤에 등록하는 것이 좋습니다.